Vacancy expired!
- Establish a cell line development platform for 23andMe for antibody candidates for cGMP manufacturing
- Perform and oversee all aspects of mammalian cell line development and early-stage cell culture development
- Lead and oversee vector construction, transfection, stable selection, cloning, expansion, characterization, and cell banking of mammalian cell lines for clinical production
- Perform laboratory experiments using a variety of CLD and cell culture technologies including single cell printing, cell imaging, and bench-scale bioreactors
- Write operational procedures, process descriptions, and technical documents
- Work with cross functional peers to execute on assignments under limited supervision
- Analyze, organize, and communicate experimental results to colleagues and senior leadership
- Extensive experience with transfection and maintenance of CHO cells lines
- Extensive knowledge of screening and characterizing clonal cell lines for use in a cGMP manufacturing
- Experience in CLD technologies including culture of CHO cells, single-cell cloning, clonality assessment, and clone screening
- Experience in cell culture in shake flasks, media development, and benchtop-scale bioreactors
- Prior experience working directly with CDMOs and 3rd party vendors is a plus
- Knowledge of downstream processing steps and interpretation of analytical results strongly preferred
- Experience with Octet/ELISA-based protein quantification is a plus
- Excellent written and oral communication skills
- ID: #23942032
- State: California Southsanfrancisco 94080 Southsanfrancisco USA
- City: Southsanfrancisco
- Salary: $54 - $55
- Job type: Contract
- Showed: 2021-12-06
- Deadline: 2022-01-18
- Category: Et cetera