Oncology Bioinformatics Genomic Data Analyst

28 Apr 2024

Vacancy expired!

Role: Oncology Bioinformatics Genomic Data Analyst

Location: SFO, CA ( 3-4 days Onsite)

Type: 10-12 months+

We are seeking a highly experienced Genomic Data Analyst to support computational research within our Oncology Bioinformatics department focused on Reverse Translation efforts in Cancer Immunology. This role will focus on applying statistical and bioinformatics analyses to our large collection of genomics data from clinical trials with the overall goal of 1) understanding the mechanisms of therapeutic response and resistance, and 2) relating findings in experimental models back to our clinical trials.

Duties
  • Perform comprehensive analysis of various clinical trial-scale NGS data sets, primarily bulk tissue RNAseq, but also WES and other clinical features.
  • Act as lead analyst on a large clinical NGS project, going from data exploration and normalization, differential gene expression, pathway analysis, to producing compelling data visualizations and presentations to colleagues.
  • Complement existing code to generate specific plots and subsequent analysis from existing project data, or perform one-off analyses of individual trials.
  • Skills
  • Strong statistical analysis and computational skills, including high level of proficiency with the R programming language and Bioconductor packages including MultiAssayExperiment, SummarizedExperiment, and Limma.
  • Relevant experience for dealing with large clinical datasets: survival analysis, batch effect detection and normalization, and confounding and covariate adjustment.
  • Experience organizing a large analysis project with organized and documented code.
  • Strong communication skills and interest in understanding and presenting analysis results in the context of Cancer Immunology.
  • A recent PhD graduate in bioinformatics, genomics, molecular epidemiology, or computational biology.
  • Experience with analysis of single cell RNA sequencing data and working with Linux-based servers is a plus, but not essential.
    • ID: #49818699
    • State: California Sanfrancisco 94101 Sanfrancisco USA
    • City: Sanfrancisco
    • Salary: $60 - $70
    • Job type: Contract
    • Showed: 2023-04-28
    • Deadline: 2023-06-05
    • Category: Et cetera