Translational Medicine Director

Job Description

The Director, Translational Medicine will develop and implement translational strategies for programs in early clinical development and continue to support clinical programs as they progress through the pipeline. The incumbent will also help to develop novel strategies to inform on dose, patient selection and combination therapies. Additional objectives are to monitor disease with biomarkers. The incumbent will be the functional expert for translational medicine in cross-functional drug development teams, lead external collaborations with partner companies and academic institutions.

Qualifications

RESPONSIBILITIES: Leads the development of project-specific goals and objectives for the Translational Development group. Designs the translational strategy for individual pipeline drugs in clinical studies Represents the Translational Medicine function in cross-functional development teams Interacts with internal assay development groups, and contract research organizations to implement biomarker development and testing Interacts with commercial functions and academic institutions to provide scientific support and support company goals Designs and facilitates implementation of the clinical biomarker strategies for company sponsored clinical trials Serves as subject matter expert for select technical biomarker solutions (tissue staining, IHC, digital pathology) and scientific discipline (cancer biology) Manages data analysis, and in collaboration with data management and bioinformatics group, delivers data and analysis for regulatory interaction and publications. management as appropriate Informs and collaborates with sample management staff to manage sample collection, shipment, and storage in collaboration Works cross-functionally within Exelixis and partners with external collaborators and vendors to achieve translational medicine goals Analyzes results from translational medicine studies and communicate to the project teams internal stakeholders Interacts with pre-clinical groups to develop to implement an integrated translational medicine strategy Provides state-of-art translational medicine solutions by keeping current on scientific and technological developments and may manage relationships with with academic institutions or partner companies

SUPERVISORY RESPONSIBILITIES: If appropriate, may directly supervises employees.

EDUCATION/Knowledge/SkillsEducation: Bachelor’s degree in related discipline and twelve plus years of related experience; or, Master’s degree in related discipline and ten plus years of related experience; or, PhD degree in related discipline and eight plus years of related experience; or, Equivalent combination of education and experience

Experience: A minimum of 10 years of experience in the biotechnology or pharmaceutical industry or the equivalent combination of education and industry experience. Deep expertise in oncogenic pathways, cancer biology, or pathology Experience in implementing biomarkers in clinical research studies is highly desirable Experience participating in clinical oncology studies with molecular targeted or immunological therapies. Excellent communication skills orally and in writing Experience in providing presentations of scientific overviews and data in appropriate context for various types of meetings (internal and external) Embrace opportunities to grow, learn and excel Ability to work independently and cooperatively with translational medicine team Ability to interact effectively across boundaries using influencing and relationship building skills.

Knowledge/Skills/Abilities: Excellent team player to build strong relationships with cross-functional leaders and peers to enable integrated and impactful translational medicine solutions Proven track record of success in translational research/translational medicine and scientific publications Expertise in a relevant platform technology (immunohistochemistry, digital pathology, flow cytometry, or genetics including assay development, data analysis, and clinical application is required Understanding of successful completion of translational projects and preparation of project related publications Effective communication skills to convey complex topics to senior management, external customers, and collaborators Has good understanding and application of technical principles, theories, concepts, and techniques related to cellular pathways in cancer biology Has good general knowledge of other related disciplines Applies strong analytical and communication skills Good public speaking and presentation skills.

JOB COMPLEXITY: Has an in-depth knowledge of the functional area. Coordinates with cross functional groups in project development areas. Exercises independent judgment in methods, techniques, and data interpretation.

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Additional Information

DISCLAIMER

The preceding job description has been designed to indicate the general nature and level of work performed by employees within this classification. It is not designed to contain or be interpreted as a comprehensive inventory of all duties, responsibilities and qualifications required of employees assigned to the job.

We are an Equal Opportunity Employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity, status as a veteran, and basis of disability or any other federal, state or local protected class.